Steel maker Caparo Industries will cut 452 jobs across its sites in the West Midlands after having entered administration earlier this month.
The announcement by administrator PwC is the latest blow to the crisis stricken UK steel manufacturing sector.
"Following a detailed review of the businesses it is with regret that we now announce 452 redundancies with immediate effect," PwC said. "Those staff affected by today's announcements have been briefed. Working closely with their representatives, the Redundancy Payments Service Rapid Response team and other agencies we will be providing support to those affected in order to address their claims for redundancy and notice."
PwC is seeking to find buyers for other sections of the struggling firm that currently employs more than 1,200 workers.
Union representatives reacted to the announcements with calls for the government to adopt a more active approach that would help support and save UK steelmaking.
"We are still of the opinion that Caparo can be saved,” said Joe Morgan, GMB Birmingham & West Midlands regional secretary. “The GMB will continue its campaign to safeguard the steel industry in the West Midlands and nationally, and will provide legal support and assistance where possible."
Unite West Midlands regional secretary Gerard Coyne said: "The closure of the Darlaston factory is another grim day for the manufacturing community in the Wolverhampton area. Following on from the news of Goodyear's planned closure, it brings down the shutters on 100 years of world class manufacturing and is a further blow to the region's skills base.”